PT-141

DISCLAIMER: This product is strictly for laboratory and in vitro research purposes only. It is not approved for human consumption, veterinary use, diagnostic, or therapeutic applications.

Product Overview

This lyophilized compound is a synthetic cyclic heptapeptide analog of naturally occurring alpha-melanocyte-stimulating hormone (α-MSH). It is formulated specifically for the investigation of melanocortin receptor agonism—primarily targeting the MC3R and MC4R pathways—in controlled laboratory environments. Current in vitro research utilizing this compound focuses on central nervous system (CNS) signaling networks, the modulation of neurovascular coupling, and receptor-mediated behavioral and physiological models. This material is supplied exclusively as a laboratory reagent for advanced structural, functional, and biochemical studies.

Technical Specifications

• CAS Number: 189691-06-3

• Molecular Formula: C₅₀H₆₈N₁₄O₁₀

• Molecular Weight: ~1025.2 g/mol

• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH

• Form: Lyophilized powder

• Purity: ≥ 98% (HPLC)

• Solubility: Soluble in sterile water or bacteriostatic water

Storage & Handling Guidelines

• Storage (Unopened): Store at -20°C, protected from light and moisture to maintain peptide stability.

• Storage (After Reconstitution): Store at 2–8°C. For optimal in vitro assay results, utilize within 14–30 days. Avoid repeated freeze-thaw cycles as this may result in peptide degradation.

CAS Number: 189691-06-3

Molecular Formula: C₅₀H₆₉N₁₅O₉

Molecular Weight: ~1025.2 g/mol

Sequence:Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH

Form: Lyophilized powder

Purity: ≥ 98% (HPLC)

Solubility: Soluble in sterile water, bacteriostatic water, or aqueous buffers

Storage (Unopened): Store at -20°C, protected from light and moisture

Storage (After Reconstitution): Store at 2–8°C, use within 14–30 days (avoid repeated freeze-thaw cycles)